Part of Our Previous Publications

  • Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate.Liu Z, Wang J, Cheng H, Ke X, Sun L, Zhang QC, Wang HW. Cell. 2018 May 17;173(5):1191-1203

  • Single particle cryo-EM reconstruction of 52 kDa streptavidin at 3.2 Angstrom resolution.
Fan X, Wang J, Zhang X, Yang Z, Zhang JC, Zhao L, Peng HL, Lei J, Wang HW. Nat Commun. 2019 Jun 3;10(1):2386. 

  • Challenges and opportunities in cryo-EM with phase plate. Wang HW, Fan X. Curr Opin Struct Biol. 2019 Oct;58:175-182.
Amyloid fibril structure of α-synuclein determined by cryo-electron microscopy. Li Y, Zhao C, Luo F, Liu Z, Gui X, Luo Z, Zhang X, Li D, Liu C, Li X. Cell Res. 2018 Sep;28(9):897-903.

  • Cryo-EM structures of human RAD51 recombinase filaments during catalysis of DNA-strand exchange.
Xu J, Zhao L, Xu Y, Zhao W, Sung P, Wang HW. Nat Struct Mol Biol. 2017 Jan;24(1):40-46. 

  • Structural insights into the secretin translocation channel in the type II secretion system. Yan Z, Yin M, Xu D, Zhu Y, Li X. Nat Struct Mol Biol. 2017 Feb;24(2):177-183. 

  • Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM. Li X, Mooney P, Zheng S, Booth CR, Braunfeld MB, Gubbens S, Agard DA, Cheng Y. Nat Methods. 2013 Jun;10(6):584-90.

  • RISE: a database of RNA interactome from sequencing experiments. Gong J, Shao D, Xu K, Lu Z, Lu ZJ, Yang YT, Zhang QC. Nucleic Acids Res. 2018 46(D1): D194-D201.

  • Transcriptome-wide interrogation of RNA secondary structure in living cells with icSHAPE. Flynn RA*, Zhang QC*, Spitale RC, Lee B, Mumbach MR, and Chang HY. Nature Protocols, 2016, 11 (2), 273-290.

  • Ainsliadimer A selectively inhibits IKKα/β by covalently binding a conserved cysteine. Dong T, Li C, Wang X, Dian L, Zhang X, Li L, Chen S, Cao R, Li L, Huang N, He S, Lei X. Nat Commun. 2015, 6:6522.

  • Binding site druggability assessment in fragment-based drug design. Yu Zhou and Niu Huang. Methods Mol. Biol. 2015, 1289:13-21.

  • Structure and Specificity of the Bacterial Cysteine Methyltransferase Effector NleE Suggests a Novel Substrate in Human DNA Repair Pathway. Yao Q, Zhang L, Wan X, Chen J, Hu L, Ding X, Li L, Karar J, Peng H, Chen S, Huang N, Rauscher FJ, Shao F. PLoS Pathog. 2014, 10(11): e1004522.

  • A structural mechanism for bacterial autotransporter glycosylation by a dodecameric heptosyltransferase family. Yao Q, Lu Q, Wan X, Song F, Xu Y, Hu M, Zamyatina A, Liu X, Huang N, Zhu P, Shao F. Elife. 2014, Oct 13;3.
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