service - SBDD B A C K
AI driven structure-based drug discovery
The Structure-Based Drug Discovery Solution（SBDD）is a holistic solution for early drug discovery with multiple product modules embedded and integrated into the SBDD Innovation Platform, which consists of three main lines.
● Large-scale virtual compound screening from identified targets for rapid discovery of promising compounds.
● Ligand-based drug discovery, which starts from existing drugs or active molecules, and uses molecular similarity to construct pharmacodynamic characteristic models for rapid discovery of active molecules.
● Reverse screening, starting from existing drugs or active molecules to predict potential targets.
Why choose ShuimuBio for SBDD?
● Supercomputing-powered in silico tools：
We can provide a complete set of computational structural biology services, including target structure analysis, virtual screening, molecular docking, ADMET properties prediction, molecular dynamics simulation and so on.
● Based on extensive Cryo-EM structural data：
Our team is a world leader in the research and application of cryo-electron microscopy technology, more and more complex protein structures are being resolved, which lays the foundation for SBDD.
● Private library：
（1）Self-built library of more than 600 million drug-forming molecules for computational chemical screening, significantly increasing the success rate of finding active molecules;
（2）self-built database of unique targets, including kinases, GPCR, ion channels, nuclear receptors, etc.
（3） Accept personalization of the database
● We have specialized laboratory resources in synthesis and biology, and provide services related to compound synthesis and activity testing
Why do you need SBDD Services?
● Compared to traditional drug discovery methods, SBDD technology enables faster, more cost-effective and efficient discovery of lead compounds.
● Predicting potential targets or identifying new uses for drugs from existing drug or active small molecule structures